Concept program
Course program, objectives and examination
The course program consists of the following elements:
- Track specific master courses: 20 ECTS (2x5 ECTS compulsory courses, 10 ECTS electives, to be selected from the list of track-specific electives)
- Minor research project (30 EC)
- Major research project (45 EC)
- Other compulsory course elements (Drug Development, essay, colloquium)
- Optional courses
10 ECTS compulsory master courses (2x5ECTS):
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Molecular toxicology (De Graaf) |
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Deepening of the knowledge on molecular processes underlying cell damage and cell death. |
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Entry requirements: |
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Basic knowledge on pharmacokinetics, metabolism and toxicology 5 |
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Advanced Pharmacokinetics (Touw) |
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Gaining more in-depth knowledge on pharmacokinetics. Including the principles of drug interactions, multi-compartment kinetics, nonlinear kinetics, physiological models (PBPK), the relationship between plasma concentration and drug effect (PKPD). Understanding the causes and consequences of inter-individual variability, the principles of individualization when dosing drugs based on age, weight or organ disorders, therapeutic drug monitoring and population pharmacokinetics. |
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Entry requirements: |
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Basic knowledge on pharmacokinetics 5 |
10 ECTS track-specific electives (in consultation with the study mentor), to be chosen from the following list:
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Pharmacovigilance (van Puijenbroek) |
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Introduction to pharmacovigilance, safety of drugs and the reporting of side effects. |
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Entry requirements: |
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Basic knowledge on pharmacoepidemiology and pharmacotherapy Competence (presentation and essay) |
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Clinical Toxicology (Touw) |
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Introduction to the scientific and practical aspects of clinical toxicology, therapeutic drug monitoring and laboratory management. |
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Entry requirements:
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Hep B-vacc., basic knowledge in pharmacotherapy and pharmacokinetics |
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Laboratory animal science (Central Animal lab) |
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Various aspects of the use of animals for experimentation are discussed, including legal aspects, biology, health, nutrition, genetics, statistics, animal models, anesthesia, alternatives and ethics. This course leads to the competence to conduct animal experiments independently. |
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Entry requirements: |
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Sufficient knowledge on physiology and anatomy 4 |
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Or Animal and human experimentation (Gerkema) Aim of this course is to prepare students starting a master project in which they participate in animal or human experimentation, with respect to methodological, practical and ethical aspects.
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Reproductive Toxicology and Epidemiology (Schuiling-Veninga) |
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Project / literature research in the field of teratogenesis. Safety and toxicity of drugs in relation to reproduction. Investigation of drugs by means of animal studies and post-marketing surveillance. |
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Entry requirements: |
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Basic knowledge in pharmacoepidemiology and toxicology |
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Innovative Dosage Forms (Frijlink) |
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The course aims to give an overview on the development of innovative dosage forms, such as controlled release preparations and dosage forms for biologicals. |
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Entry requirements: |
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none |
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Proteomics (Bisschof)
